Abstract
BACTERIOLOGIC REVIEW Impetigo (contagiosa) was definitely described as a clinical entity in 1864 and 1869 by Tilbury Fox. 1 Kohn, 2 in 1871, concluded that it was due to an organism of the hyphomycete group. In this he was supported by Behrend, 3 but this view has been generally abandoned in recent years. Demme, 4 in 1886, was the first to cultivate a diplococcus from a case of acute contagious pemphigus. Bockhart, 5 in 1887, concluded that impetigo was caused by Staphylococcus pyogenes aureus and albus . In 1893, M. C. Leroux 6 took cultures from 120 children with cases of contagious impetigo. He obtained seventy positive cultures, finding divers varieties of Staphylococcus pyogenes and streptococci . He called attention to the contagious character of the disease and its appearance among children in the same family and after contact. Studying impetigo experimentally, he inoculated a series of children, reproduced typical lesions, and
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