Abstract
Background: The Baylor Gyro permanently implantable centrifugal pump (PI 710 pump) achieved 90 day survival in an animal experiment as a biventricular assist device without thrombus formation. The aim of this study is to confirm the high antithrombogenicity of PI 710 from the viewpoint of impeller movement. Materials and Methods: The mock circulation loop consisted of an aortic and left atrial chamber, pulsatile pump and PI 710. This circuit was filled with 37% glycerin/water. The pulsatile pump simulated the natural heart while the PI 710 was the left ventricular assist device with left ventricular drainage. An acrylic pump was used in order to observe the impeller. The RPM was changed from 1200 to 2600 rpm, and the impeller movement was examined. Results: The impeller floated up and down synchronized to the pulsation from about 1600 to 1800 rpm (impeller was up during diastole and down during systole). And over 1800 rpm, the impeller contacted the top hearing. In these two conditions, the bottom bearing of the impeller moved to the ouflow side during systole and to the counterside during diastole. Conclusion: The PI 710 impeller was dynamically suspended during pulsatile circulation, and was dependent on RPM. These authors anticipated that these movements have a dynamic effect for antithrombogenicity.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
