Abstract
Objectives. To identify the characteristics of impairments to spatial working memory and their neurophysiological correlates in patients with mild depressive disorders. Materials and methods. A total of 30 patients (right-handed) with ICD-10 diagnoses of Mood Disorder (F31.3, F32.0, F33.0, F34.1) were studied before treatment started. Mean age was 37 ± 8 years. The control group consisted of 30 mentally and somatically healthy subjects (mean age 32 ± 7 years). Spatial working memory was investigated using the Corsi Block-Tapping test. Electroencephalography (EEG) studies were also run for analysis of spectral power in the θ, α, and β ranges. Results and conclusions. Decreases in spatial working memory were seen in mild depressive disorders and this corresponded to high EEG θ-rhythm power in the frontal and occipital areas and α-rhythm power in the frontal cortex.
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