Abstract

Profiles of nonesterified and esterified cholesterol in ovary, liver and serum were studied in sexually mature Cyprinus carpio exposed to sublethal concentrations of phenol and sulfide for 45 days. Phenol caused a gradual and significant increase in nonesterified cholesterol in ovary and liver with a concomitant rise in the hepatosomatic index (HSI), while the gonadosomatic index (GSI) decreased gradually. Phenol exposure had little effect on serum nonesterified cholesterol. Sulfide exposure, on the other hand, resulted in a gradual and significant decrease in only ovarian nonesterified cholesterol and an increase in both hepatic and serum nonesterified cholesterol. Using [4- 14C]cholesterol as a tracer, it was found that for 45-day exposure, sulfide had an adverse effect on the transport of cholesterol from circulation to ovary. Both the pollutants had an inhibitory effect on the conversion of radiolabelled cholesterol to steroidal products.

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