Abstract
The pituitary response to luteinzing hormone-releasing hormone (LH-RH) was studied in lactating and nonlactating spayed ewes. During the 1st 4 weeks postpartum the release of LH in response to LH-RH increased progressivily to a constant pattern in lactating animals. However as the pattern of LH release was indistinguishable from controls it was concluded that prolactin does not alter the ability of the pituitary to release LH in response to LH-RH. Similarly the LH response to LH-RH in nonlactating spayed ewes was not modified by hyperprolactinemia. Another experiment was performed to determine whether the positive feedback effect of estradiol on the hypothalamus was impaired by high prolactin levels. The most effective dose of estra diol-17beta was rendered ineffective by thyrotopin-releasing hormone induction of hyperprolactinemia. The results suggest that high prolactin levels are involed in the suppression of ovulation during lactation.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
