Abstract
Alcohol use disorder (AUD) is a common addictive psychological disease in modern society. AUD can induce a cluster of health and working memory (WM) problems, including Korsakoff's syndrome, irrational decision-making, impaired executive function, and impulsivity. Neuropsychological evidence shows that prefrontal cortex (PFC) function is impaired in AUD patients and their dopamine (DA) level is unstable. The present essay aims to discuss the relationship between AUD and WM from three points of view. Firstly, the behavioral and neuropsychological deficits of AUD subjects were summarized and categorized in detail. Secondly, the potential mechanism of WM impairment is discussed. Thirdly, various kinds of neuropsychological and behavioral treatments for AUD were critically reviewed and evaluated. While the pharmacological treatment was supported by various empirical studies and validated in different subtypes of AUD, the emerging behavioral therapy was revealed to be more secure and side-effect free than traditional medications.
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