Impaired Glucose Tolerance-A cross Sectional Study among Middle Aged Individuals

Abstract

Background and Objectives: Diabetes mellitus represents a spectrum of metabolic disorders which has become a major health challenge worldwide. Impaired glucose tolerance (IGT) forms a grey area between diabetes mellitus and normal individuals. IGT has a greater risk of developing future diabetes. To explore the prevalence of IGT in normal healthy individuals, to find correlation between IGT and BMI and family history. Materials and Methods: About 100 randomly selected subjects of middle aged group 25-45 years of both sexes were selected. Exclusion criteria include hypertension, diabetes oral contraceptives pill users, thyroid disorders, smokers and alcoholics. Oral glucose tolerance test (GTT) was done in all subjects. If 2-hour post glucose concentration was between 140- 199mg%, then the person was labelled as IGT. Variables such as Height, Weight, body mass index and family history were also taken. All the data were analyzed using chi-square, Fischer’s exact and two tailed Pearson correlation. Results: The prevalence of IGT was 16%. Age specific prevalence in subjects below 35 years was 7% and above 35 years was 9%. Interpretation and Conclusion: The prevalence of IGT was 16%. Subjects with positive family history and BMI had positive correlation with IGT. But there was no age specific prevalence between two selected groups. Key words: Diabetes mellitus, Body mass index, Impaired glucose tolerance