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British Journal of Clinical PharmacologyVolume 17, Issue 5 p. 595-597 Free Access Impaired enzyme induction by rifampicin in the elderly [letter] Y Twum-Barima, Y Twum-BarimaSearch for more papers by this authorT Finnigan, T FinniganSearch for more papers by this authorAI Habash, AI HabashSearch for more papers by this authorRD Cape, RD CapeSearch for more papers by this authorSG Carruthers, SG CarruthersSearch for more papers by this author Y Twum-Barima, Y Twum-BarimaSearch for more papers by this authorT Finnigan, T FinniganSearch for more papers by this authorAI Habash, AI HabashSearch for more papers by this authorRD Cape, RD CapeSearch for more papers by this authorSG Carruthers, SG CarruthersSearch for more papers by this author First published: May 1984 https://doi.org/10.1111/j.1365-2125.1984.tb02397.xCitations: 36AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References Adelman, R. C. (1975). Impaired hormonal regulation of enzyme activity during ageing. Fed. Proc., 34, 179– 181. Ahmad, D., Mathur, P., Ahuja, S., Henderson, R. & Carruthers, S. G. (1979). Rifampicin-quinidine interaction. Br. J. dis. Chest, 73, 409– 410. Crooks, J., O'Malley, K. & Stevenson, I. H. (1976). Pharmacokinetics in the elderly. Clin. Pharmacokin., 1, 280– 296. Cusack, B., Kelly, J. G., Lavan, J., Noel, J. & O'Malley, K. (1980). Theophylline kinetics in relation to age: The importance of smoking. Br. J. clin. Pharmac., 10, 109– 114. Eichelbaum, M. & Spannbrucker, N. (1977). Rapid and sensitive method for the determination of antipyrine in biological fluids by high-pressure liquid chromatography. J. Chromatogr., 140, 288– 292. Gelehrter, T. D. (1976). Enzyme induction. New Engl. J. Med., 294, 522– 526, 589–595, 646–651. Greenblatt, D. J., Sellers, E. M. & Shader, R. I. (1982). Drug disposition in old age. New Engl. J. Med., 306, 1081– 1088. Kato, R. & Takanaka, A. (1968). Effect of pheno-barbital on electron transport system, oxidation and reduction of drugs in liver microsomes of rats of different age. J. Biochem. (Tokyo), 63, 406– 408. Kato, R., Vassanelli, P., Frontino, G. & Chiesara, E. (1964). Variation in the activity of liver microsomal drug-metabolising enzymes in rats in relation to age. Biochem. Pharmac., 13, 1037– 1051. Kroboth, F. J., Kroboth, P. D. & Logan, T. (1983). Phenytoin-theophylline quinidine interaction. New Engl. J. Med., 308, 725. Marshall, W. J. (1978). Enzyme induction by drugs: its relevance to clinical biochemistry. Ann. clin. Biochem., 15, 55– 64. O'Malley, K., Crooks, J., Duke, E. & Stevenson, I. H. (1971). Effect of age and sex on human drug metabolism. Br. med. J., 3, 607– 609. Salem, S. A. M., Rajjayabun, P., Shepherd, A. M. M. & Stevenson, I. H. (1978). Reduced induction of drug metabolism in the elderly. Age Ageing, 7, 68– 73. Twum-Barima, Y. & Carruthers, S. G. (1981). Quinidine-rifampicin interaction. New Engl. J. Med., 304, 1466– 1469. Urbano, A. M. (1983). Phenytoin-quinidine interaction in a patient with recurrent ventricular tachyarrhythmias. New Engl. J. Med., 308, 225. Citing Literature Volume17, Issue5May 1984Pages 595-597 ReferencesRelatedInformation

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