Impaired Anti-oxidant Defense Mechanism in Central Eales Disease

Abstract

A tertiary care center-based, case-control study evaluated the status of oxidative stress, enzymes involved in the antioxidant defense and membrane fluidity in platelets of 6 cases with central Eales disease and 5 healthy controls. Significant differences were observed between malonaldialdehyde, superoxide dismutase and catalase levels in the cases and controls. Enhanced oxidative stress, is consistent with an emerging view that antioxidant defenses decline in association with the disease process.