IMPACT OF WHOLE BLOOD DONATION ON BLOOD PRESSURE IN STAGE 1 HYPERTENSION

Abstract

At present, blood donation and donors’ health are the imperatives of the healthcare system. 
 The aim of the paper is to study the impact of blood donation on blood pressure in hypertensive donors.
 Materials and Methods. During 12 months, the authors examined and followed-up 100 frequent whole blood donors, aged 40.3±7.5, with stage 1 hypertension. The donors did not receive any drug treatment for hypertension. The authors also monitored erythrocyte and hemoglobin levels, and 24-hour blood pressure. Statistica 10 software was used for statistical data analysis.
 Results. The study revealed that the dynamics of blood pressure depended on anemia, which could develop as a result of blood donations. Thus, one year after the 1st blood donation, we observed an increase in 24-hour mean SBP by 4.0 % (p<0.05), 24-hour mean DBP by 3.9 % (p<0.05), daytime SBP variability by 33 % (p<0.05), and daytime DBP variability by 28.8 % (p<0.05) in 17 blood donors with hypertension in case of anemia progression. Pathological BP rhythms also increased. We noted a statistically significant (p<0.05) decrease in SBP and DBP, as well as SBP and DBP variability in 83 donors with hypertension who did not develop anemia in 12 months.
 Conclusion. Whole blood donors with stage 1 hypertension, who do not undergo antihypertensive therapy, demonstrate positive blood pressure dynamics, whereas those who develop anemia as a result of blood donations show negative blood pressure dynamics.