Abstract
Irisin, a hormone discovered in 2012, has gained attention for its potential role in regulating metabolism and promoting fat burning. This study was conducted on 180 women from Najaf Governorate/Iraq with T2DM who were divided into two main groups: the first group 90 T2DM with vitamin D deficiency and the second group 90 T2DM without vitamin D deficiency. Serum 25(OH)D and irisin levels were analyzed for the purpose of knowing the effect of vitamin D status on circulating irisin in relation to lipid profile and glycemic control in women with type 2 diabetes.The finding of the current study has been signified the effect of vitamin D deficiency may on serum irisin level in T2DM women. The vitamin D-deficient T2DM women had lower irisin levels than normal vitamin D T2DM women consistent with our hypothesis.
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