Abstract
Thestrategy for thetreatment of gastric cancer (GC), in particular theuse of theextended surgical interventions in different countries varies. Thedifferent proportion of specific molecular GC subtypes in various populations frequently is not taken into account for comparing treatment outcomes. This pilot study analyzes theassociation of survival of GC patients after theextended combined surgical interventions depending on themolecular subtype of thetumors. An improved survival for patients with diffuse cancer types (p53-, VEGFR+, HER2/neu+, Ki-67+ phenotype) was demonstrated. Theauthors propose their point of view on theimportance of recognizing GC molecular heterogeneity.Key Words: gastric cancer, molecular classification, tumor biology.
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