Abstract
Objective To investigate the impact of transvaginal natural orifice transluminal endo-scopic surgery（NOTES）-assisted laparoscopic nephrectomy on female sexual function and quality of life . Methods This was a prospective study on the change of female sexual function and quality of life of female patients who underwent transvaginal NOTES-assisted laparoscopic nephrectomy from May .2011 to Nov. 2012.A total of 42 cases were included in this study （28 of them with severe hydronephrosis , non-functio-ning kidney , 11 with pyelonephrosis , 1 with renal tuberculosis , 1 with duplex kidney complicated with hy-dronephrosis, and 1 with renal angiomyolipoma ）.The mean age was 36.9±5.3 （26-45） years, and the mean body mass index was 21.7±2.6 （14.7 to 27.1） kg/m2.Twenty-four cases were operated on the left side, 18 cases on the right .The female sexual function and quality of life were assessed before and 4 months, 7 months and 1 year after surgery using the Female Sexual Function Index （FSFI） questionnaire and the MOS 36-item Short-Form Health Survey （SF-36）, respectively. Results The mean FSFI of 42 cases preoperatively and 4 months, 7 months and 1 yr postoperatively were 27.74 ±4.34, 27.19 ±4.49, 28.54±4.23, and 28.68 ±4.19, respectively.There was no statistically significant difference among them （F=1.111, P=0.346）.Compared with that of preoperation , the physical function, vitality, metal health, body pain, and general health of the patients were improved , but the role-physical, role-emotion and social function were not improved at postoperative month 4 and month 7 （P〈0.05）.Each item of SF-36 was im-proved after postoperative 1 year （ P〈0.05） . Conclusions Transvaginal NOTES-assisted laparoscopic ne-phrectomy does not cause negative effect on the female sexual function .The quality of life can be improved after operation .The physical function is improved at early stage , and the psychological function as well . Key words: Natural orifice transluminal endoscopic surgery; Transvaginal; Female sexual func-tion; Quality of life
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