Abstract

Introduction: Coronary angiography is a two-dimensional (2D) imaging modality and thus is limited in its ability to represent complex three-dimensional (3D) vascular anatomy. Lesion length, bifurcation angles/lesions, and tortuosity are often inadequately assessed using 2D angiography due to vessel overlap and foreshortening. 3D Rotational Angiography (3DRA) with subsequent reconstruction generates models of the coronary vasculature from which lesion length measurements and Optimal View Maps (OVM) defining the amount of vessel foreshortening for each gantry angle can be derived. This study sought to determine if 3DRA-assisted percutaneous coronary interventions resulted in improved procedural results by minimizing foreshortening and optimizing stent selection. Methods: 26 patients with obstructive coronary artery disease were included. Rotational angiographic acquisitions were performed and a 3D model was generated from two images greater than 30° apart. An optimal view map identifying the least amount of vessel foreshortening and overlap was derived from the 3D model. 3DRA derived and operator predicted optimal working view and stent lengths were compared. Results: 3DRA assistance significantly reduced target vessel foreshortening when compared to operator’s choice of working view for PCI (2.99% ± 2.96 vs. 9.48% ± 7.56, p=0.0001). The operators concluded that 3DRA recommended better optimal view selection for PCI in 14 of 26 (54%) total cases. In 9 (35%) of 26 cases 3DRA assistance facilitated stent positioning. 3DRA based imaging prompted stent length changes in 4/26 patients (15%). Conclusion: The use of 3DRA positively impacts the performance of percutaneous coronary interventions by optimizing working views through reductions in vessel foreshortening and overlap and assisting in stent positioning by improvements in stent and lesion measurements.

Highlights

  • Coronary angiography is a two-dimensional (2D) imaging modality and is limited in its ability to represent complex three-dimensional (3D) vascular anatomy

  • The operators concluded that 3D Rotational Angiography (3DRA) recommended better optimal view selection for Percutaneous Coronary Intervention (PCI) in 14 of 26 (54%) total cases

  • Coronary angiography remains the preferred modality for characterization of atherosclerotic coronary artery disease in contemporary cardiology

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Summary

Introduction

Coronary angiography is a two-dimensional (2D) imaging modality and is limited in its ability to represent complex three-dimensional (3D) vascular anatomy. The traditional strategy used to minimize projection imaging inaccuracies is to acquire multiple views of a vessel segment for a more complete angiographic assessment. This assessment, comes at the cost of increased radiation, contrast exposure, and procedural time. Optimal view selection is contingent on both individual operator skill and experience as well as unique patient anatomy and is often based purely on a trial-and-error technique. To overcome these obstacles, innovative angiographic techniques have been devised, most notably, rotational angiography (RA) with three-dimensional modeling (3DCA)

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