Abstract
Background:This study compared features of the Vero4DRT system with those of conventional systems, focusing on the total treatment time and patient safety. Methods: Individual treatment times for brain stereotactic radiotherapy (SRT) and stereotactic body radiation therapy (SBRT) were compared among the Vero4DRT, Novalis, and Clinac iX systems. The mean total treatment time was calculated by summing the entire time required for the radiation treatment. The total treatment time for both brain SRT and SBRT with non-coplanar fields was markedly shorter with the Vero4DRT system than the others. Results: For SBRT, the treatment time with the Vero4DRT system was reduced by 40%, compared with the time using a Clinac iX (13.8 vs. 20.3 min). For SRT, the treatment time with Vero4DRT was 20% shorter than with the Novalis system. With Vero4DRT, all treatments were completed within 14 min, with a significant reduction in the kV-image acquisition and image merging times. Conclusion: The total treatment time using the Vero4DRT system was significantly shorter compared with conventional options in clinical settings; the shorter treatment time also offered the advantages of minimal intrafractional body movement, as well as better patient throughput.
Highlights
Developed by Kyoto University, Mitsubishi Heavy Industries, and the Institute of Biomedical Research and Innovation [1,2,3], the Vero4DRT system is a high-precision radiotherapy system with dynamic tracking irradiation
The treatment times with the Vero4DRT for stereotactic body radiation therapy (SBRT) using a non-coplanar field was markedly shorter, with treatment provided in about three-fifths of the time required for the Clinac iX system (13.8 vs. 20.3 min)
The SBRT irradiation method and treatment time per patient for the Vero4DRT system were shorter than those measured for the Novalis system (13.8 vs. 16.1 min); the Vero4DRT system was functioning in cone-beam Computed tomography (CT) imaging mode
Summary
With conventional general-purpose linear accelerators, the operator must enter the treatment room to rotate the couch before beginning non-coplanar field irradiation. With the Vero4DRT system, there is no need to move the couch; seamless treatment can be provided remotely from the control room, shortening the treatment time. The total treatment time is important factor for high-precision treatments and these features of the Vero4DRT system may effectively reduce. This study compared features of the Vero4DRT system with those of conventional systems, focusing on the total treatment time and patient safety
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