Impact of the SARS-COV-2 Pandemic on the Endovascular Treatment of Acute Stroke – an Italian Single-Center Experience

Abstract

ObjectivesThe SARS-CoV-2 pandemic greatly influenced the overall quality of healthcare. The purpose of this study was to compare the time variables for acute stroke treatment and evaluate differences in the pre-hospital and in-hospital care before and during the SARS-CoV-2 pandemic, as well as between the first and second waves. Materials and methodsObservational and retrospective study from an Italian hospital, including patients who underwent thrombectomy between January 1st 2019 and December 31st 2020. ResultsOut of a total of 594 patients, 301 were treated in 2019 and 293 in 2020. The majority observed in 2019 came from spoke centers (67,1%), while in 2020 more than half (52%, p < 0.01) were evaluated at the hospital's emergency room directly (ER-NCGH). When compared to 2019, time metrics were globally increased in 2020, particularly in the ER-NCGH groups during the period of the first wave (N = 24 and N = 56, respectively): “Onset-to-door”:50,5 vs 88,5, p < 0,01; “Arrival in Neuroradiology – groin”:13 vs 25, p < 0,01; “Door-to-groin”:118 vs 143,5, p = 0,02; “Onset-to-groin”:180 vs 244,5, p < 0,01; “Groin-to-recanalization”: 41 vs 49,5, p = 0,03. When comparing ER-NCGH groups between the first (N = 56) and second (N = 49) waves, there was an overall improvement in times, namely in the “Door-to-CT” (47,5 vs 37, p < 0,01), “Arrival in Neuroradiology – groin” (25 vs 20, p = 0,03) and “Onset-to-groin” (244,5 vs 227,5, p = 0,02). ConclusionsDuring the SARS-CoV-2 pandemic, treatment for stroke patients was delayed, particularly during the first wave. Reallocation of resources and the shutting down of spoke centers may have played a determinant role.