Abstract

Impact of Some Heavy Metals Toxicity on Behaviour, Biochemical and Histopathological Alterations in Adult Rats

Highlights

  • Animal welfare is an issue for veterinary science and animal psychology and for biochemical, agriculture, zoology and companion animal fields because animal welfare is a socially constructed idea and it is not a permanently fixed idea (Watanabe, 2007)

  • The objective of this study was to investigate the effect of lead acetate and aluminum chloride toxicities on welfare aspects through measuring its effect on some welfare indicators as behaviour, biochemical parameters as well as histopathological changes in adult rats

  • Animal behaviour and health are the most effective animal-based indicators, with researchers/ advisers scoring the highest means in case of animal behaviour good feeding and housing are from the farm level indicators which are important for welfare improvement (Averós et al, 2013)

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Summary

Introduction

Animal welfare is an issue for veterinary science and animal psychology and for biochemical, agriculture, zoology and companion animal fields because animal welfare is a socially constructed idea and it is not a permanently fixed idea (Watanabe, 2007). Lead is a one of the major heavy metals known to be toxic to mammals. It had many sources as metallic lead present in storage batteries, paints and rubbish dumps in areas near lead industrial establishments and from the industrial applications especially the addition of vast quantities of September 2016 | Volume 4 | Issue 9 | Page 494 NE Academic. Aluminum is the third most prevalent element and approximately 8% of total mineral components in the earth’s crust (Verstraeten et al, 2008) It is broadly distributed in the environment and widely used in daily life causing its easy exposure to animals and human. It was reported that aluminum exposure can lead to impairments in glucose utilization, free-radical-mediated cytotoxicity and lipid peroxidation (Chinoy, 2001)

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