Abstract
PURPOSE: Pulmonary arterial hypertension (PAH) is a group of diseases characterized by an impressive increase in pulmonary vascular resistances (PVR) that causes severe right ventricular (RV) dysfunction. The prognosis is related to the severity of hemodynamic impairment. Because the pathophysiologic model is an afterload mismatch we hypotisize that the best RV adaption should be a “concentric” hypertrophy (i.e. high RV mass/volume ratio).
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