Abstract
The term “Pemphigus” is derived from the Greek word Pemphix means “bubble or blister” and Vulgaris means “common”. It is a potentially life-threatening disease that causes erosions and blisters of the skin and mucous membranes. It is a chronic, rare, intra-epidermal bullous disease with a potentially fatal outcome and was originally named by Wickman in the years 1791. Pemphigus is an uncommon disease with an incidence rate ranging from 0.5 to 3.2 per 100,000 per year. In this article, we discussed a rare case report on the impact of Rituximab in the management of Pemphigus Vulgaris. The Inj. Rituximab was found to be more effective in treating Pemphigus Vulgaris along with supportive medication. By considering different literature, it has been concluded that Pemphigus Vulgaris has a relapse in nature. So, ongoing monitoring and adjustment of treatment are often necessary to manage the condition. Patient must require regular follow-up appointments with his healthcare professional to monitor the disease actively and adjust the treatment as necessary depending upon their clinical manifestations.
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