Abstract

In stereotactic body radiotherapy (SBRT) for lung tumors, the use of internal target volume (ITV) has enabled a consistent account of patient-specific tumor movements during dose delivery. However, the dose to lung tissue is typically calculated in a static volume that equals to the lung volume minus ITV, which does not take into account the excursions of lung tissue into the high dose regions in ITV. The aim of this study was to investigate the impact of respiratory motion on the calculation of lung dose and on the assessment of lung toxicities.

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