Impact of Pharmacist Assisted Patient Counselling in Improving Medication Adherence and Quality of Life in Epileptic Patients

Abstract

The objective was to assess the impact of patient counselling on quality of life and medication adherence. A prospective interventional observational study was conducted. Demographics and other relevant data were documented. Medication adherence and Quality of life were evaluated using the Medication adherence scale and Quality of life in epilepsy -31 questionnaire respectively. Multivariate analysis with a Chi-square test was used to observe the association between different variables and Antiepileptic drug adherence. We also evaluated the correlation coefficient between socio-demographic factors and Quality of life in epilepsy-31 sub-scales. Among 109 epilepsy patients, 17 patients had a high level of adherence, 52 patients with medium adherence, and 40 patients with low adherence to Anti-epileptic drug therapy. The mean (Standard deviation) score of the first and second follow-up of the Medication adherence scale was 4.50(1.80) and 5.23 (1.29) respectively which showed significant improvement in adherence. However, no significant difference was observed between adherence and gender, marital status, past medical history, family history, and social functioning. Significant changes were seen in the quality of life during follow-up. This study found that the majority of patients with epilepsy have optimal rates of Anti-epileptic drug therapy adherence and that forgetfulness is the primary reason for nonadherence among patients with epilepsy.