Abstract
684 Background: In patients (pts) with breast cancer, PET-CT is increasingly being used for staging, multimodality treatment planning, monitoring response to therapy, and follow-up. Our goal was to determine the utility of PET-CT for initial staging and treatment planning of pts with breast cancer. Methods: We performed a retrospective study of 32 breast cancer pts who underwent integrated PET-CT for initial staging between May 2003 and November 2004. Evidence of disease was determined clinically and histopathologically. Results: Thirty-two patients (age 30 to 73 years, mean 51) were included in this analysis. Clinical stage prior to PET-CT: stage 0 (2 pts), stage I (1 pt), stage II (18 pts), and stage III (11 pts). In detecting the primary breast mass, PET-CT had a false negative rate of 13%. A breast mass was not identified in 4 pts: 2 with DCIS, 1 with invasive ductal carcinoma < 1cm in size, and 1 with invasive lobular carcinoma 3 cm in size. Axillary lymph node (ALN) metastases were evident in 21 pts...
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