Impact of percutaneous coronary intervention on regional myocardial function in patients with chronic stable angina

Abstract

Objective To determine the impact of percutaneous coronary intervention (PCI) on regional myocardial function by tissue Doppler echocardiography (TDE) in patients with chronic stable angina and normal baseline ejection fraction. Background The impairment of left ventricular longitudinal function may precede the circumferential dysfunction in patients with ischemia and this impairment cannot be detected by conventional echocardiography. Successful PCI may improve this impairment and this can be detected using TDE. Patients and methods Between October 2013 and August 2015, this follow-up study in our teaching hospital included 25 consecutive patients with chronic stable angina and normal baseline ejection fraction who underwent PCI and were studied by TDE before, and 1 day and 6 weeks after PCI. Myocardial tissue peak velocities (E', A' and S') were recorded at the septal, lateral, anterior, and inferior angles of the mitral annulus and at the lateral tricuspid annulus. Results There was a highly significant improvement in E', A' and S' velocities of the mitral valve 1 day and 6 weeks after PCI at all sites: septal, lateral, anterior, and inferior (P > 0.001). Also, there was a highly significant improvement in the E' and A' velocities of the tricuspid valve 1 day and 6 weeks after PCI (P > 0.001). The S' velocity of the tricuspid valve showed a significant improvement on the first day after PCI (P = 0.02), which increased 6 weeks' after PCI to become highly significant (P > 0.001). Conclusion TDE parameters of diastolic and systolic functions improve early after successful PCI, and this effect persists up to 6 weeks after PCI.