IMPACT OF OVERWEIGHT AND OBESITY ON BLOOD PRESSURE CONTROL AMONG HYPERTENSIVE PATIENTS (RESULTS FROM NATURE HTN)

Abstract

Objective: Given the increase of sedentarily and bad diet in our life, the prevalence of obesity and overweight has remarkably increased among the most of population, last years. We aimed in this work to assess the impact of weight on blood pressure control in hypertensive patients based on data from the Tunisian national registry Nature HTN Design and method: Nature HTN is a national multicentric study conducted by the Tunisian society of cardiology and including hypertensive patients who consulted their doctors during one month in 2019. We collected clinical data, blood pressure measurements and lab test. We defined Overweight. Results: We enrolled 25890 hypertensive patients, with female predominance (SR = 1.2) and mean age 64.4 ± 12.2 year-old. The hypertension was newly diagnosed in 2286 patients (8.8%) and known more than six months in 23601 persons. The mean BMI was 28.1 ± 4.57. Obesity and overweight were observed respectively in 25.8% and 44.6%. Female were significantly more obese than male (34.7% vs 17.6%, p < 10-3). Patients with uncontrolled BP were more frequently obese (30.5% vs 27.4%, p < 10-3) and have a higher BMI. Among patients with overweight or obesity there was a correlation the prevalence of uncontrolled BP and the severity of obesity (71.5% in overweight people, 74.8 in patient with moderate obesity, 79.4% in patients with severe obesity, p = 0.001). Moreover obesity was found as independent predictor of non-controlled BP in our cohort (OR = 1.14, 95% CI[1.07–1.21]. Conclusions: Obesity is a health problem growing and should keep in mind when treating patients with hypertension because it is a strong predictor of non-controlled BP.