Abstract

We read with interest the article of Garbino et al. on the impact of enteral versus parenteral nutrition on fungal infections in patients requiring ventilation and selective digestive decontamination (SDD) on the intensive care unit (ICU). 1 Garbino J. Pichard C. Pichna P. Pittet D. Lew D. Romand J.A. Impact of enteral versus parenteral nutrition on the incidence of fungal infections a retrospective study in ICU patients on mechanical ventilation with selective digestive decontamination. Clin Nutr. 2004; 23: 705-710 Abstract Full Text Full Text PDF PubMed Scopus (11) Google Scholar Although the fungal infection rate in the patients receiving enteral nutrition was about half that in the parenteral group, the difference was not statistically significant (9.9% vs. 17.3%, P = 0.32 ), due to design and small sample size. Additionally, the two groups were not comparable as the 29 parenterally fed patients were iller with peritonitis and pancreatitis receiving broad spectrum antibiotics, hence increasing the risk of fungal infection.

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