Abstract
BackgroundAntimicrobial resistance (AMR), especially carbapenem-resistant Pseudomonas aeruginosa (CRPA), causes a serious increase in morbidity, mortality and costs. Medical professionals play an important role in curbing AMR. Previous studies overlooked the impact of workload on the relationship between medical professionals and AMR. This study aimed to explore the relationship between medical professionals and the CRPA rate as well as the moderating effect of medical professionals’ workload on this relationship.MethodsA provincial-level panel dataset from 2014 to 2017 was constructed. Medical professionals were measured by the numbers of physicians, registered nurses, pharmacists, and clinical microbiologists per 1000 population. Workload was measured by the number of daily physician visits. Fixed effect model and hierarchical regression analysis were performed to explore the moderating effect of workload on medical professionals and the CRPA rate.ResultsThe numbers of physicians, registered nurses, pharmacists and clinical technicians were significantly negative associated with the CRPA rate (coef. = − 0.889, − 0.775, − 1.176, and − 0.822; P = 0.003, 0.003, 0.011, and 0.007, respectively). Workload had a significant and positive moderating effect on physicians, registered nurses, pharmacists, clinical technicians and the CRPA rate (coef. = 1.270, 1.400, 2.210, and 1.634; P = 0.004, 0.001, 0.035, and 0.003, respectively).ConclusionsIncreasing the number of medical professionals may help curb the CRPA rate. Measures aimed at reducing medical professionals’ workload should be implemented to further improve CRPA performance.
Highlights
Antimicrobial resistance (AMR), especially carbapenem-resistant Pseudomonas aeruginosa (CRPA), causes a serious increase in morbidity, mortality and costs
What is the action path of workload on this relationship? Since CRPA has arisen great concern, this study explored the relationship between medical professionals and the CRPA rate as well as the moderating effect of workload in this relationship using 2014–2017 provincial balanced panel data in China
Considering physicians, pharmacists, and clinical microbiologists are involved in the diagnosis, prescription, and prudent use of antimicrobials, and registered nurses are consistent executors, they are regarded as the core members of AMR stewardship [8, 9, 21]
Summary
Antimicrobial resistance (AMR), especially carbapenem-resistant Pseudomonas aeruginosa (CRPA), causes a serious increase in morbidity, mortality and costs. Previous studies overlooked the impact of workload on the relationship between medical professionals and AMR. This study aimed to explore the relationship between medical professionals and the CRPA rate as well as the moderating effect of medical professionals’ workload on this relationship. Many countries are facing the challenge of antimicrobial resistance (AMR). AMR, carbapenem-resistant Pseudomonas aeruginosa (CRPA), threatens global public health security [3]. As a main pathogen of healthcare-associated infections (HAIs), the treatment of Pseudomonas aeruginosa (P. aeruginosa) is often challenging due to its intrinsic non-susceptibility to many antimicrobials [4]. The increasing rate of CRPA worldwide limits its therapeutic options as well as aggravates the costs and the risk of mortality [6, 7]. According to the WHO, Carbapenems are considered as critically important antimicrobials (CIAs) and have become important solution to serious P. aeruginosa infections [5, 7]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
