Abstract

Background: Chronic headache is one of the most common pain conditions, often leading to symptomatic drug overuse. The aim of this study was to provide data on symptomatic drug consumption in an Italian outpatient population and to describe how the clinical picture of headache may change after headache experts take charge of the care of affected individuals.Methods: A total of 199 adults complaining of chronic headache were recruited through 32 pharmacies in the Pavia health district. Participants underwent four evaluations: a baseline assessment (T0) and three follow-up evaluations performed by a neurologist at 3, 6, and 12 months (T3, T6, and T12, respectively). On each occasion, they underwent a complete neurological assessment and received therapeutic adjustments to achieve better management of their headache.Results: On the basis of a preliminary telephone interview, the prevalence rates of chronic headache and medication overuse headache (MOH) were 16 and 12%, respectively. At 12 months of follow-up, we observed a significant decrease in the frequency of attacks (T0: 9 ± 9/month vs. T12: 2 ± 2/month; p < 0.001), in the number of days/month with headache (T0: 11 ± 9 vs. T12: 4 ± 4; p < 0.001) and in single attack duration (T0: 34 ± 30 h vs. T12: 10 ± 19 h; p < 0.001). Careful headache management resulted in a significant decrease in analgesic consumption (T0: 12 ± 16 vs. T12: 4 ± 6 doses/month; p = 0.014) and a significant increase in quality of life, measured using the Migraine Disability Assessment Scale (MIDAS) and Headache Under-Response to Treatment (HURT) scales (p < 0.001).Conclusions: Headache management by a specialist is more effective than self-treatment, resulting in an overall benefit for headache patients.

Highlights

  • Headache is a common pain condition, responsible for varying degrees of disability depending on the frequency, duration and intensity of the attacks

  • Careful headache management resulted in a significant decrease in analgesic consumption (T0: 12 ± 16 vs. T12: 4 ± 6 doses/month; p = 0.014) and a significant increase in quality of life, measured using the Migraine Disability Assessment Scale (MIDAS) and Headache Under-Response to Treatment (HURT) scales (p < 0.001)

  • Headache management by a specialist is more effective than self-treatment, resulting in an overall benefit for headache patients

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Summary

Introduction

Headache is a common pain condition, responsible for varying degrees of disability depending on the frequency, duration and intensity of the attacks. The high disability level, in terms of headache intensity and frequency, and the consequent reduced physical activity are often associated with a higher tendency to the symptomatic usage of drugs, which may turn into real medication overuse [6]. Only about 20% of young people suffering from headache appear to consult a physician to get advice [20], and self-medication in the general population of headache sufferers (44%) [21] may be another possible reason for headache chronification. In this context, the pharmacy might be the first contact point for headache advice [20]. The aim of this study was to provide data on symptomatic drug consumption in an Italian outpatient population and to describe how the clinical picture of headache may change after headache experts take charge of the care of affected individuals

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