Abstract
Beta-lactam (BL) allergy labels may lead to suboptimal antibiotic treatment and the unnecessary use of broad-spectrum antibiotics [ [1] Jeffres M.N. Narayanan P.P. Shuster J.E. Schramm G.E. Consequences of avoiding β-lactams in patients with β-lactam allergies. J Allergy Clin Immunol. 2016; 137 (Epub 20151211): 1148-1153https://doi.org/10.1016/j.jaci.2015.10.026 Abstract Full Text Full Text PDF PubMed Scopus (109) Google Scholar ]. Despite the need for BL allergy delabeling being emphasized, it has not been universally implemented in Korea, and there is a lack of understanding of the effects of BL allergy delabeling on patient care and healthcare costs. Surgical prophylactic antibiotics account for most of the antibiotics used in hospitals, and BL antibiotics are the first-line agents for surgical prophylaxis [ [2] Blumenthal K.G. Peter J.G. Trubiano J.A. Phillips E.J. Antibiotic allergy. Lancet. 2019; 393 (Epub 20181214): 183-198https://doi.org/10.1016/S0140-6736(18)32218-9 Abstract Full Text Full Text PDF PubMed Scopus (264) Google Scholar ]. Therefore, we aimed to assess the impact of BL allergy reports on antibiotics prescription patterns, clinical outcomes, and economic costs in patients receiving systemic antibiotics for surgical prophylaxis.
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