Abstract

With the development of assisted reproductive technology (ART), more and more hepatitis B virus (HBV)-infected couples have their own children successfully; however,vertical transmission of HBV in ART, especially father-to-child transmission, cannot be avoided. The mechanism of attachment and penetration of HBV into human sperm is still not known. Therefore, understanding the state and mechanism of HBV infection of sperm and the impact of HBV on sperm parameters, following up the ART outcome in man with HBV infection are helpful to solve the fertility problem and to control father-to-child vertical HBV infection.

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