Abstract
Antiplatelet therapy without anticoagulation has reduced hemorrhagic/vascular complications following stent implantation. However, a substantial number of patients still suffer from complications due to the widespread increase in the number of stent implantations. While heparin neutralization is one of the most simple and inexpensive methods to reduce the complications, with demonstrated short-term safety and feasibility [ 1 Ducas J. Chan M.C. Miller A. et al. Immediate protamine administration and sheath removal following percutaneous coronary intervention: a prospective study of 429 patients. Catheter Cardiovasc Interv. 2002; 56: 196-199 Crossref PubMed Scopus (22) Google Scholar , 2 Briguori C. Di Mario C. De Gregorio J. et al. Administration of protamine after coronary stent deployment. Am Heart J. 1999; 138: 64-68 Abstract Full Text Full Text PDF PubMed Scopus (34) Google Scholar , 3 Pan M. Suarez de Lezo J. Medina A. et al. In-laboratory removal of femoral sheath following protamine administration in patients having intracoronary stent implantation. Am J Cardiol. 1997; 80: 1336-1338 Abstract Full Text Full Text PDF PubMed Scopus (62) Google Scholar ], its affect on long-term outcome (restenosis) is not known.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
