IMPACT OF HEAD AND NECK RADIOTHERAPY ON THE LONGEVITY OF DENTAL ADHESIVE RESTORATIONS: SYSTEMATIC REVIEW/META-ANALYSIS

Abstract

Objective: To analyze the evidence regarding the impact of head and neck radiotherapy (HNRT) on the longevity of dental adhesive restorations. Study Design: Data extraction was performed regarding percentage of restoration failure among dental adhesive materials including glass ionomer cements (GICs), resin-modified glass ionomer cements (RGMICs), and resin composites (RC). The search was performed at PubMed, Scopus, and Embase. Results: Four studies met the inclusion criteria. All included studies reported results regarding class V restorations. Overall, RC presented lower failure rates in 2 years (30%) compared with RGMICs (41%) and GICs (57%). Meta-analysis showed that GIC risk of failure was greater than in RGMICs (risk ratio of 1.71). RC presented lower risk of failure compared with GIC and RGMIC (risk ratios of 1.93 and 1.30, respectively). Three studies reported results regarding fluoride compliance, which presented a negative impact on survival rates of GIC and RGMIC while presenting a positive impact on RC restorations. Conclusions: Results suggest that RC restorations associated with fluoride gel compliance seems to be the best alternative for restoring class V lesions in post-HNRT patients. However, the results showed moderate certainty of evidence, which justify the need for randomized clinical trials regarding this subject. Objective: To analyze the evidence regarding the impact of head and neck radiotherapy (HNRT) on the longevity of dental adhesive restorations. Study Design: Data extraction was performed regarding percentage of restoration failure among dental adhesive materials including glass ionomer cements (GICs), resin-modified glass ionomer cements (RGMICs), and resin composites (RC). The search was performed at PubMed, Scopus, and Embase. Results: Four studies met the inclusion criteria. All included studies reported results regarding class V restorations. Overall, RC presented lower failure rates in 2 years (30%) compared with RGMICs (41%) and GICs (57%). Meta-analysis showed that GIC risk of failure was greater than in RGMICs (risk ratio of 1.71). RC presented lower risk of failure compared with GIC and RGMIC (risk ratios of 1.93 and 1.30, respectively). Three studies reported results regarding fluoride compliance, which presented a negative impact on survival rates of GIC and RGMIC while presenting a positive impact on RC restorations. Conclusions: Results suggest that RC restorations associated with fluoride gel compliance seems to be the best alternative for restoring class V lesions in post-HNRT patients. However, the results showed moderate certainty of evidence, which justify the need for randomized clinical trials regarding this subject.