Impact of First 10 Years of Post Menopause on Muscle Function, Muscle Mass and Bone Mineral Density in Adult Women

Margarete Noriko Kochi,Nise Ribeiro Marques,Cristine Homsi Jorge Ferreira ,Francisco José Albuquerque De Paula ,Gustavo De Carvalho Da Costa ,João Batista Ribeiro Da Silva Reis ,Daniela Cristina Carvalho De Abreu

doi:10.4172/2329-9509.1000151

Margarete Noriko Kochi, Nise Ribeiro Marques + Show 5 more

Open Access

https://doi.org/10.4172/2329-9509.1000151

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Abstract

Background: Previous studies suggested that the early identification of risk factors for the development of osteoporosis should reduce medical complications, which are associated with increased morbidity and mortality in older women. Purpose: The present study had the objective to identify the relationship between Bone Mineral Density (BMD), anthropometric characteristics, years of post-menopause, strength, muscle mass and the performance on functional tests in up 10 years postmenopausal women. Methods: Participated of the study fifty-eight post menopause women who were assessed by dual-energy X-ray absorptiometry (DXA) of femoral neck and whole-body to determine BMD and relative skeletal muscle index (RSMI). Also, the muscle strength was assessed by handgrip strength test (HGS) and two functional tests were performed: Timed Up-and-Go (TUG) and Five-Times-Sit-To-Stand (FTSTS). Results: The results shown a positive correlation between BMD and weight (r = 0.54, p < 0.05), BMD and BMI (r = 0.56, p < 0.05), BMD and RSMI (r = 0.38, p < 0.05). Conclusions: The findings of the present study demonstrated a correlation between muscle mass and BMD and also shown that anthropometric characteristics, such as higher weight and BMI were correlated with higher BMD and muscle mass in up 10 years postmenopausal women.

Highlights

Age-related changes affect the muscle-skeletal system resulting in decline of muscle and bone mass, especially in women and the bone decline may result in a metabolic bone disease called osteoporosis
Previous studies suggested that the early identification of risk factors for the development of osteoporosis should reduce medical complications, which are associated with increased morbidity and mortality in older women [1,2,3]
The results demonstrated that was a positive correlation between Bone Mineral Density (BMD) and weight (r = 0.54, p < 0.05), BMD and BMI (r = 0.56, p < 0.05), BMD and relative skeletal muscle index (RSMI) (r = 0.38, p < 0.05)

Summary

Introduction

Age-related changes affect the muscle-skeletal system resulting in decline of muscle and bone mass, especially in women and the bone decline may result in a metabolic bone disease called osteoporosis. Osteoporosis is a common and costly disease, characterized by the decline of bone mineral density and changes on bone microarchitecture, which leads to weakness on the resistance of bones and higher risk of fractures in older women [1,2,3]. Beyond the bone mass decline, decrements on blood levels of oestrogen may cause age-related muscle mass loss [1,3,7,8]. Purpose: The present study had the objective to identify the relationship between Bone Mineral Density (BMD), anthropometric characteristics, years of post-menopause, strength, muscle mass and the performance on functional tests in up 10 years postmenopausal women

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Results

Conclusion