Abstract

Coptis chinensis Franch (CCF) is commonly used in herbal remedies in Traditional Chinese Medicine (TCM) owing to its observed antimicrobial and anticancer effects in clinical medicine [1]. As an individual herb, CCF has exhibited potent inhibition on a number of bacteria including Escherichia coli in vitro conditions. The alkaloid components in CCF have been suggested to be the bioactive ingredients. The aim of our study was to investigate: 1) if there is any inhibitory effect on food and animal pathogens such as E. coli, Listeria and Mycobacterium smegmatis, 2) the efficiency of our routine extraction procedures for removal of the known maker alkaloids from CCF.

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