Abstract
Background: Entamoeba histolytica is a unicellular, protozoon parasite of humans. It moves by a jelly-like tongue-like protrusion of the cytoplasm “pseudopodium”. Infections by this parasite lead to distinct clinical manifestations, including diarrhea, mild abdominal pain, loss of appetite, fatigue, dysentery, and hepatic liver abscess. Methods: In this paper, we discussed about Entamoeba histolytica disease, its epidemiology, pathophysiology, hygiene, causes, risk factors, clinical manifestation and complications, method of transmission, diagnosis, treatment, and incubation period in human body. Results: It is the second leading cause of death. It was diagnosed by taking a complete history and testing stool samples for the presence of E. histolytica cysts. It was treated pharmacologically and surgically. Conclusion: We have concluded that the Entamoeba histolytica is an infection mostly related to fecal-oral transmission due to poor hand hygiene, defecation into water sources such as rivers, and being near animals, and gay or bisexual males due to the risk of fecal-oral contamination through oral and anal sex. It is the second leading cause of death from parasitic intestinal disease worldwide. Key Words: Entamoeba histolytica, epidemiology, pathophysiology, hygiene, incubation period, human body
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