Abstract
Sleep disturbances are common in patients with mental disorders. Sleep disturbances, in particular insomnia, are widespread in depression. Depressed patients have a lot of sleep complaints that are often confirmed by polysomnography. Most antidepressants impair sleep, so drugs that help to restore sleep are of particular value in clinical practice. Agomelatine (valdoxan) rapidly improves sleep in depressed patients by making it easier to fall asleep, increasing total sleep time, duration of rapid eye movement (REM), and slow-wave sleep (SWS), and improving functioning during the day.
Highlights
Проблемы со сном широко распространены среди пациентов, страдающих психическими расстройствами
Sleep disturbances are common in patients with mental disorders
Depressed patients have a lot of sleep complaints that are often confirmed by polysomnography
Summary
Проблемы со сном широко распространены среди пациентов, страдающих психическими расстройствами. Влияние антидепрессантов разных классов на регуляцию процессов сна и бодрствования при депрессии. Сокращение общей продолжительности медленноволнового (slow-wave sleep, SWS) сна, особенно его III стадии (дельта-сон);
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