Abstract
To assess impact of different antibiotic regimens on patients with respiratory tract infection, we establish a randomized controlled trial for comparison of different antibiotic regimens. From May 2019 to February 2021, we collected valid data from 182 patients in the hospital. This study consisted of 3 steps. First, we invited the patients with respiratory tract infection who meet the inclusion criteria. Also, patients were divided into control group (n=98) and intervention group (n=84) according to the antibiotic regimen they received. Second, we collected the data by questionnaires, including basic patient characteristics, treatment period, treatment cost, and treatment effect. Third, we analyze the data by software. In this study, the less days of treatment period and less payment of treatment in intervention group patient than control group patients, that their results between were significantly different. Also, treatment effect of two antibiotic regimens were similar, that the rates of treatment effective were no significantly different. In summary, we found that the patients who received levofloxacin lactate sodium chloride injection treatment had shorter treatment period and less treatment cost than the patients who received ceftazidime treatment, but their treatment effects were similar.
Highlights
Lower respiratory infections (LRI) are a major public health problem in patients of all ages
Patients were divided into control group (n=98) and intervention group (n=84) according to the antibiotic regimen they received
We collected the data by questionnaires, including basic patient characteristics, treatment period, treatment cost, and treatment effect
Summary
Lower respiratory infections (LRI) are a major public health problem in patients of all ages. The reports indicated that hospitals received more than 420 million of patients with lower respiratory infections [1, 2]. Antibiotics can provide effective treatment to patients with lower respiratory infections, there are still 1.4 million deaths a year among patients [3, 4]. Doctor often use antibiotics to treat patients with lower respiratory infections. Different antibiotic regimens provided different treatment effect and treatment cost in similar patients with lower respiratory infections [7,8,9]. Those are reasons why exploring Impact of different antibiotic regimens on patients with respiratory tract infection
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