Abstract
Impact of Delirium on Postoperative Frailty and Long Term Cardiovascular Events After Cardiac Surgery
Highlights
Since 2013, our hospital has been working on the DOPPO project, which aims to provide ambulatory discharge for hospitalized frail elderly persons
We examined the relationship between walking ability and prognosis in elderly chronic heart failure (CHF) patients
After adjustment for potential cofounders, multivariate analysis showed the independent predictors of major adverse cardiac events (MACE) to be Postoperative delirium (POD) (HR, 3.45; 95% CI, 1.62–6.90; P=.01) and postoperative frailty (HR, 3.40; 95% CI, 1.52–7.94; P=.004)
Summary
Skeletal muscle plays an important role in pathogenesis of exercise intolerance in patients with chronic heart failure (HF). The clinical significance of skeletal muscle mass in patients with acute decompensated HF (ADHF) remains unclear. Methods: We assessed lean body mass by dual energy X-ray absorptiometry in 108 patients with ADHF (age 72 ± 11, left ventricular ejection fraction 37 ± 15%, B-type natriuretic peptide levels on admission 732 [394–1315] pg/ml). ADHF patients were followed until occurring CV events (CV death, nonfatal myocardial infarction, ischemic stroke, unstable angina, HF re-hospitalization, or coronary revascularization). Results: Forty eight patients developed CV events (median follow-up, 17 months). Kaplan-Meier analysis demonstrated a significantly higher probability of CV events in the low ASMI group than those in
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