Impact of dairy consumption on essential hypertension: a clinical study.

Jean-Philippe Drouin-Chartier,Benoît Lamarche,Luc Poirier,Patrick Couture,Iris Gigleux,André J Tremblay

doi:10.1186/1475-2891-13-83

Jean-Philippe Drouin-Chartier, Benoît Lamarche + Show 4 more

Open Access

https://doi.org/10.1186/1475-2891-13-83

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Journal: Nutrition journal	Publication Date: Aug 14, 2014
Citations: 59	License type: cc-by

Affiliation: Université Laval

Abstract

BackgroundSeveral studies have presented evidence suggesting that dairy consumption has beneficial effects on blood pressure (BP) in healthy subjects; however, only a few studies have examined this possibility in patients with established essential hypertension using ambulatory blood pressure monitoring. The objective of this study was to investigate how consuming dairy products impacts mean daytime systolic and diastolic BP in men and women with mild to moderate essential hypertension.MethodsEighty-nine men and women with systolic BP ≥ 135 mm Hg and ≤ 160 mm Hg and diastolic BP ≤ 110 mm Hg were enrolled in this single-blind, randomized, cross-over, controlled study. Participants had to incorporate three daily servings of dairy products or control products equivalent in macronutrients and sodium during four-week treatment phases. Twenty-four hour ambulatory BP and endothelial function were assessed at screening and at the end of each dietary phase.ResultsThe consumption of three daily servings of dairy products led to a significant reduction in mean daytime ambulatory systolic BP (-2 mm Hg; P = 0.05) in men compared with readings after the control phase. In women, dairy consumption had no effect on ambulatory systolic BP. Moreover, endothelial function was significantly improved by dairy consumption in the whole cohort.ConclusionThese data indicate that the consumption of three daily servings of dairy products have beneficial effects on daytime systolic ambulatory BP compared to a heart-healthy, dairy-free, diet in men with mild to moderate essential hypertension.Trial registrationThis trial is registered at clinicaltrials.gov as NCT01776216.

Highlights

Several studies have presented evidence suggesting that dairy consumption has beneficial effects on blood pressure (BP) in healthy subjects; only a few studies have examined this possibility in patients with established essential hypertension using ambulatory blood pressure monitoring
The consumption of three daily servings of dairy products led to a significant reduction in mean daytime ambulatory systolic BP (−2 mm Hg; P = 0.05) in men compared with readings after the CONTROL phase (Table 4)
The results of the current study suggest that dairy consumption has beneficial effect on endothelial function of mild to moderate hypertensive subjects

Summary

Introduction

Several studies have presented evidence suggesting that dairy consumption has beneficial effects on blood pressure (BP) in healthy subjects; only a few studies have examined this possibility in patients with established essential hypertension using ambulatory blood pressure monitoring. The objective of this study was to investigate how consuming dairy products impacts mean daytime systolic and diastolic BP in men and women with mild to moderate essential hypertension. Arterial hypertension, which is defined as mean ambulatory daytime systolic blood pressure (BP) ≥ 135 mm Hg and diastolic BP ≥ 85 mm Hg, is one of the most important risk factors for cardiovascular and renal disease [1]. Diet is a key factor for preventing and treating elevated BP [6,7] Healthy eating patterns, such as the Dietary Approaches to Stop Hypertension (DASH), vegetarian diets or the Mediterranean diet, have been shown to have beneficial effects in controlling BP [8,9,10]. Calcium and magnesium or low intakes of sodium and alcohol may contribute at different levels to lower BP [11,12]

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