Abstract
The past decade has been one of rapid advance for Multiple Breath Washout (MBW) as a tool to detect early obstructive lung disease. Consensus recommendations for both researchers and manufacturers were developed for MBW test performance and device design [1], including technical standards specific to the preschool age range [2]. MBW research has transitioned from custom built research equipment to validated commercial MBW devices [3]. Evidence has continued to be published outlining improved sensitivity of its main outcome, the Lung Clearance Index (LCI), to detect both early cystic fibrosis (CF) lung disease and the subsequent beneficial response to interventions, compared to spirometry.
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