Impact of COVID 19 on Preterm Rupture of Membrane

Abstract

Background: The majority of perinatal research on COVID-19 currently focuses on the pregnancy consequences of SARS-CoV-2-infected women, including as cesarean sections, fetal distress, premature delivery, and even maternal mortality. However, it is currently uncertain how the COVID-19 pandemic would negatively affect premature membrane rupture. Aim of the Study: The aim of this study was to assess the impact of Covid 19 on preterm rupture of membrane. Methods: This cross-sectional study was conducted in department of obstetrics and gynaecology, Care Medical College Hospital, Dhaka, Bangladesh from 2021 to 2022. Total 100 pregnant women were included in this study. Where group A represented Covid 19 affected (n=50) and group B represented Not affected by Covid 19 (n=50). Result: In this study, mean age was 30.9 years (SD±8.5 years) in group A and 29.3 years (SD±7.5 years) in group B. Mean gestational age was 37.55 weeks (SD±2.42 weeks) in group A and 36.10 weeks (SD±3.08 weeks) in group B. Both groups had history of preterm delivery (2%), 8% of group A and 4% of group B had history of postpartum hemorrhage, and 22% of group A and 2% of group B had other family members affected. The commonest mode of delivery in both groups; 74% and 62% in group A and group B respectively. 16% in group A and 8% in group B had premature rupture of membranes and 4% in group A and 2% in group B had preterm premature rupture of membranes. Table V shows the neonatal outcome. Neonatal Covid 19 positive was 4% in group A. 18% of group A and 10% of group B were admitted in NICU. Neonatal mortality was 4% in group A and 2% in group B. Conclusion: Preterm births are more likely to occur in pregnant COVID-19 patients and the disease has an impact on NICU admissions. Premature rupture of membranes at term and preterm are more frequent in patients with COVID-19.