Abstract
COVID-19 is a highly contagious disease caused by Severe Acute Respiratory Syndrome CoronaVirus-2 (SARS-CoV-2); which is a novel single-stranded positive RNA infection which consist of cytokines that activate the pathogenic systems that cause high respiratory pain condition, and adversely affect on multiple body organ in humans as per their immunity standards to fight against the virus. SARS-CoV-2 enters the host cell through Angiotensin-Converting Enzyme 2 (ACE 2). ACE 2 is a sub-part of the Renin-Aldosterone Angiotensin System (RAAS), intelligently communicated in the body's kidney, heart, lungs, and malignant tissues. The malfunctioning of RAAS in the body leads to hypertension, cardiovascular sicknesses, endocrine system and negatively affects a brain-body communication channel. Treatments on the RAAS structure, 'thiazolidinedione's and smoking, toxemia, kidney, lungs disorder due to the SARS-CoV-2 attack on the host cell and notice the behavioral changes of body organs the arrival of cytokines that causes multi-organ damage. This paper involves the study of the effects of coronavirus disease on multiple body-organ injuries.
Highlights
A novel 'coronavirus disease-19 (COVID-19)''' was unknown until December ’2019 outbreak in Wuhan, China, and it was announced as a pandemic by WHO on 11th march 2020 [1]
Asymptomatic or mild symptoms of COVID-19 found in some people could be recovered without hospitalization in 7-14 d, but ~20% of cases have severe symptoms, which required critical care, morbidity and mortality of COVID-19 are primarily associated with severe acute respiratory distress syndrome (SARDS) due to acute viral pneumonia [5]
We are assuming that the contact of Angiotensin-Converting Enzyme 2 (ACE 2) and its upregulation in various neurotic conditions making patients more helpless to SARSCoV-2 contamination and can add to an expansion in mortality
Summary
A novel 'coronavirus disease-19 (COVID-19)''' was unknown until December ’2019 outbreak in Wuhan, China, and it was announced as a pandemic by WHO on 11th march 2020 [1]. The infected cell starts damaging the alveoli responsible for the exchange of oxygen and CO2, the severe illness with SARS-CoV-2, when the respiratory system containing the disease enters the upper respiratory part, as the virus contamination increases, the sickness can cause more damages to the lungs due to pneumonia [18].
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
