Impact of COVID-19 on Multiple Body Organ Failure: A Review

Abstract

COVID-19 is a highly contagious disease caused by Severe Acute Respiratory Syndrome CoronaVirus-2(SARS-CoV-2) which is a novel single-stranded positive RNA infection which consist of cytokines thatactivate the pathogenic systems that cause high respiratory pain condition and adversely effect on multiplebody organ in humans as per their immunity standards to fight against the virus. SARS-CoV-2 enters thehost cell through Angiotensin-Converting Enzyme 2 (ACE 2). ACE 2 is a sub-part of the Renin-AldosteroneAngiotensin System (RAAS) which is intelligently communicated in the kidney, heart, lungs and fatal tissuesof the body. The malfunctioning of RAAS in the body leads to hypertension, cardiovascular sicknesses,endocrine system and also affect negatively a brain body communication channel. Treatments on the RAASstructure, thiazolidinedione’s and smoking, toxaemia, kidney, lungs disorder due to the SARS-CoV-2 attackon the host cell and notice the behavioural changes of body organs on the arrival of cytokines that causesmulti-organ damage. This paper involves the study of the effects of coronavirus disease on multiple bodyorgandamages.