Impact of Comorbidities and Outcomes In Patient with Alcoholic Cardiomyopathy with and Without Chronic Liver Disease

Abstract

Background Alcohol consumption can lead to alcoholic cardiomyopathy (ACM) as well as chronic liver disease (CLD). Studies suggested an association between ACM and CLD, however, there is paucity of data on how CLD influences in-hospital outcomes in subjects with ACM. Methods This retrospective cohort study based on the Nationwide Inpatient Sample included all patients above 18 years who have ACM with or without CLD from 2011 to 2017. Statistical analyses were done comparing ACM with and without CLD. Multivariate logistic regression was used to evaluate the impact of CLD on in-hospital outcomes. Results A total of 128,081 individuals had a diagnosis of ACM, with 15% with CLD. ACM without CLD were older (median 57 vs. 55 years), with a higher number of males (87% vs. 84.5% p Conclusion Although we found individuals with ACM without CLD have higher burden comorbidities and in-hospital cardiovascular complications, patients with ACM and CLD have higher in-hospital all-cause mortality.