Abstract
To determine predictive factors which affect local and regional recurrence of T1-2N0-1M0 oral tongue carcinoma (OTC). Records of 42 patients with T1-2N0-1 M0 OTC were reviewed. The clinical characteristics, histo-pathological data, disease recurrence and survival rate were analyzed. Descriptive statistics and Kaplan-Meier survival analysis were used. The median follow up was 38months. The 2-year overall survival and disease-free survival rates were 85.7 and 55.6% respectively. At the 2year analysis, there were surgical margin <5mm (p value=0.01), tumor thickness >7mm (p value=0.03), perivascular and perilymphatic invasion (p value=0.01) affected on local recurrence and perivascular and perilymphatic invasion were also predictors for regional recurrence (p value=0.04). The surgical margin status, tumor thickness, perivascular and perilymphatic invasion represented significant predictive factors for local recurrent OTC. Postoperative adjuvant therapy should be considered in these groups.
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