Abstract

Background Recent data have demonstrated a lower mortality in acute ST-elevation myocardial infarction (STEMI) patients with previous treatment with statins, especially in patients with high risk profiles. Moreover, a significant reduction in enzymatic infarct size in non-STEMI patients could be observed. However, systematic data of the impact of chronic statin pre-treatment on myocardial damage and reperfusion injury assessed with the gold standard cardiac magnetic resonance imaging (CMR) are lacking. The aim of our prospective study was therefore to assess the effects of a chronic statin pre-treatment on myocardial damage as assessed by CMR in patients with acute reperfused STEMI. Methods

Highlights

  • Recent data have demonstrated a lower mortality in acute ST-elevation myocardial infarction (STEMI) patients with previous treatment with statins, especially in patients with high risk profiles

  • Systematic data of the impact of chronic statin pre-treatment on myocardial damage and reperfusion injury assessed with the gold standard cardiac magnetic resonance imaging (CMR) are lacking

  • The aim of our prospective study was to assess the effects of a chronic statin pre-treatment on myocardial damage as assessed by CMR in patients with acute reperfused STEMI

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Summary

Introduction

Recent data have demonstrated a lower mortality in acute ST-elevation myocardial infarction (STEMI) patients with previous treatment with statins, especially in patients with high risk profiles. Impact of chronic statin-pretreatment on myocardial damage as assessed by Cardiac Magnetic Resonance findings in patients with acute ST-elevation myocardial infarction Georg Fuernau*, Ingo Eitel, Steffen Desch, Suzanne de Waha, Gerhard Schuler, Holger Thiele From 15th Annual SCMR Scientific Sessions Orlando, FL, USA.

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