Impact of carbocyclic sugar-based myo-inositol on conventional surfactants

Abstract

Surfactants and inositol are examples of eco-friendly components that seem to be sustainable in chemistry. The hydrophilic portion of myo-inositol (MI) may be effective in increasing the superficial activity of the micellar systems. It is possible to modify and enhance the aggregation properties of surfactants by selecting suitable additives such as MI. The impact of carbocyclic sugar-based MI on conventional surfactants such as Triton X-100 (TX-100), cetyltrimethylammonium bromide (CTAB), and sodium dodecyl sulfate (SDS) was performed by electrical conductivity, viscometer, colorimetry, stalagmometer, dynamic light scattering (DLS) and FTIR methods. The main focus of this paper was to determine the critical micelle concentration (CMC), hydrodynamic radii (Rh), zeta potential (ζ), various interfacial parameters viz., the surface tension at CMC (γCMC), the surface pressure at CMC (πCMC), the efficiency of adsorption pC20, the minimum surface area per molecule (Amin), the maximum surface excess concentration (Гmax), and thermodynamic parameters i.e., the standard Gibbs free energy of adsorption (ΔG°ads), the standard Gibbs free energy of transfer (ΔG°trans), the standard Gibbs free energy of air–water interface (ΔGsmin), the standard Gibbs free energy of micellization (ΔGom), the standard Gibbs free energy of micellization per alkyl tail (ΔG°tail). A significant decrease in the CMC values of all conventional surfactants was reported with the addition of different concentrations of MI (mM) and its conformational study by colorimetric method. The higher negative values of ΔG°m and ΔG°ads have been shown the micellization and adsorption properties became more spontaneous. Relative viscosity-based rheological behaviour was calculated for various surfactant-MI systems. The DLS and FTIR spectra were used to reveal the improved micellization behaviour of conventional surfactant-MI systems. The FTIR data showed that the CTAB-MI and SDS-MI systems have significantly influenced the stretching frequency as compared to the TX-100-MI system. The present works will apply to drug delivery, agrochemical, molecular biology, and pharmaceutical sciences.