Abstract

Important declines have been observed in urological cancer-related mortality in recent decades, mainly due to improvements in treatments of prostate cancer, less exposure to tobacco smoking as well as occupational carcinogens of kidney and bladder. However, because of global population ageing, age-related urinary tract cancers are expected to increase in the near future despite improved primary prevention, early detection and more efficient treatment. In this article, renal cell carcinoma (RCC), kidney transplantation, cancer and acute kidney injury (AKI), lung cancer and chronic kidney disease (CKD), breast cancer, prostate cancer, cervix cancer and brain cancer and their associations with kidney function and structure have been discussed. In conclusion, kidney and cancers have interaction with each other. Kidney carcinoma can be metastasizing to other organs as well as other cancer to kidney. Therefore, it is recommended to consider the potential effect of kidney functions and interaction with other cancers in each malignancy.

Highlights

  • Important declines have been observed in urological cancer-related mortality in recent decades, mainly due to improvements in treatments of prostate cancer, less exposure to tobacco smoking as well as occupational carcinogens of kidney and bladder [1]

  • The search was conducted by using combinations of the following keywords and/or their equivalents; end-stage renal disease, renal cell carcinoma, kidney transplantation, cancer, acute kidney injury (AKI), lung cancer, chronic kidney disease, breast cancer, prostate cancer, cervix cancer, brain cancer, renal transplantation, renal replacement therapy and adenocarcinoma

  • It is reported that Sunitinib could be effective and safe to considerable inhibition of brain metastasis with no important adverse effect in Cancers kidney function patients with brain metastases from renal cell carcinoma (RCC) [13]

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Summary

Introduction

Important declines have been observed in urological cancer-related mortality in recent decades, mainly due to improvements in treatments of prostate cancer, less exposure to tobacco smoking as well as occupational carcinogens of kidney and bladder [1]. Because of global population ageing, age-related urinary tract cancers are expected to increase in the near future despite improved primary prevention, early detection and more efficient treatment [1]. Active surveillance from renal failure and cancer patients could be declined the mortality from these diseases [2]. Approximately 2% to 5% of all kidney cancers may originate from inheritance, with about 10 potential cancer susceptibility to increase the risk of renal cancer, with red flags of multiplicity of tumors, unusual or pathogenic pathology or early age of onset [3]. The involvement of kidney with other tumors may present as isolated solitary lesions which is not an end-stage renal disease (ESRD), that is sometimes the first and only site

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