Impact of BMGIM Music Therapy on Emotional State in Patients with Inflammatory Bowel Disease: A Randomized Controlled Trial.

Vicente Alejandro March-Luján,José Luis Platero Armero,María Capilla-Igual,Xavier Cortés,José Enrique De La Rubia Ortí,María Josefa-Rodríguez-Morales,José María Paredes Arquiola,Vicente Prado-Gascó,Ana Monzó-Gallego,José María Huguet

doi:10.3390/jcm10081591

Abstract

Background. Patients with inflammatory bowel disease (IBD) have a high prevalence of emotional disturbances which worsen the symptoms of the disease. As a therapeutic alternative that is part of a comprehensive care alongside medication, the Bonny Method of Guided Imagery and Music (BMGIM) music-assisted therapy has achieved promising emotional improvements in patients with chronic diseases. The objective of the study was to determine the impact of a treatment based on a BMGIM group adaptation on patients with inflammatory bowel disease (IBD) and their emotional state, therefore analyzing state of mind, quality of life, anxiety, depression, immunocompetence as a marker of well-being, and levels of acute and chronic stress. Methods. Longitudinal, prospective, quantitative, and experimental study including 43 patients with IBD divided into an intervention group (22 patients), who received eight sessions over eight weeks, and a control group (21 patients). A saliva sample was taken from each patient before and after each session in order to determine cortisol and IgA levels. Similarly, a hair sample was taken before the first and after the last session to determine the cumulative cortisol level. All molecules were quantified using the ELISA immunoassay technique. In addition, patients completed several emotional state questionnaires: HADS, MOOD, and CCVEII. Results. An improvement was observed in the following states of mind: sadness, fear, anger, and depression. No significant effect was observed in state of mind in terms of happiness or anxiety, in the levels of cortisol in hair, and in patients’ perceived quality of life. A reduction in cortisol was observed in saliva, although this did not significantly affect the IgA titer. Conclusions. BMGIM seems to improve the emotional state of patients with IBD.

Highlights

The results obtained in our study after the intervention based on a Bonny Method of Guided Imagery and Music (BMGIM) group adaptation in patients with inflammatory bowel disease (IBD) show significant improvements in most of the psychopathologic variables analyzed, as well as in acute physiological stress levels determined from cortisol levels in saliva
The BMGIM approach in particular has proven to be very successful in reducing stress in patients with various diseases [54,58,60]
As for IBD patients, we infer it is necessary to carry out more studies in which the number of sessions, application time, or intensity are increased, trying to establish which is the protocol that can achieve significant improvements in this variable or, on the contrary, confirm that BMGIM does not improve quality of life in these patients

Summary

Introduction

Inflammatory bowel disease (IBD) includes Crohn’s disease (CD) and ulcerative colitis (UC) It is characterized by its chronic course, as well as by a fluctuating and creativecommons.org/licenses/by/ 4.0/). Recurrent clinical course [1] that impacts on mental health [2] In this sense, these patients have psychological manifestations [3,4,5,6,7,8,9]. The evaluation of an ill person’s perception of well-being is closely related to immunocompetence In this sense, immunoglobulin A (IgA) is a key part of the immune system that acts against threats, especially in autoimmune diseases such as IBD. This immunoglobulin is positively correlated with the well-being of the patient [23]

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Results

Conclusion