Abstract

<b>Background:</b> Chronic rhinosinusitis with nasal polyps (CRSwNP) is responsible for an increased overall disease burden among patients with asthma. Biologics are an establish therapy for severe asthma and its efficacy in patients with co-existent CRSwNP has been a subject of interest. <b>Aim:</b> To compare the impact of biologic therapy in severe asthma patients with and without CRSwNP. <b>Materials and methods:</b> Multicenter retrospective study of severe asthma patients under biologic therapy in 2020. We compared 20 patients with CRSwNP with a randomized sample of 34 patients without CRSwNP. <b>Results:</b> 54 severe asthma patients were included and both groups were homogeneous concerning sex, age, BMI, smoking habits and BMI. <b>Discussion:</b> Before treatment patients with CRSwNP had more asthma exacerbations with more short-term use of OCS;after biologics, they experience a greater reduction in the total number of prescribed OCS courses acquiring an exacerbation pattern similar to those under biologics without CRSwNP.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.