Abstract
Neuroplastic alterations of cortical excitability can be accomplished by non-invasive brain stimulation with transcranial direct currents (tDCS). Excitability alterations can last from some minutes for up to more than 24h after plasticity induction. However, substantial interindividual variability does exist with regard to the duration and magnitude of the effects. The reasons for this variability have not been systematically explored. In a retrospective analysis in 22 healthy humans, we analyzed the dependence of tDCS-induced motor cortex plasticity from baseline excitability, as defined by the transcranial magnetic stimulation (TMS) intensity required to induce motor evoked potential amplitudes (MEP) of the size of 1 mV.
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